Exact(1)
Macrozone-specific markers in the non-volatile metabolite data set classified according to their chemical class and macrozone relevance; the classification is the same as used in Fig. 3.
Similar(59)
Using PSI-BLAST, we identified a set of 15,788 sequences with potential relevance to the classification of Hox-proteins.
The 2-year follow-up of the EPHEYL cohort should reinforce the relevance of the classification.
Drug-drug interactions were sorted by clinical relevance using the Classification System of the Department of Pharmacology, Hospital Huddinge, Stockholm, Sweden [ 19].
Our opinion is that this approach will increase the probability for clinicians to appropriate themselves such a classification; of course, the relevance of the classification in 5 classes should be prospectively tested in usual care conditions.
Across these various samples coming from both Caucasoid and non-Caucasoid populations, we investigated the relevance of the classification of HLA-DRB1 alleles proposed by Tezenas du Montcel and colleagues [ 11] regarding susceptibility to RA.
In the case of univariate PLS applied to binary classification problems, the weight vector w1 = (w11, ……, w p1) defining the first latent component may be used to order the p genes in terms of their relevance for the classification problem.
As RA severity outcomes as well as anti-CPP information were not collected in the framework of the 13th IHWG, we were not able to discuss the relevance of the classification of HLA-DRB1 alleles proposed by Tezenas du Montcel and colleagues [ 8] regarding RA severity or autoantibody production in the various Caucasoid and non-Caucasoid population samples included in the present study.
In the present association study, we investigated the relevance of the classification of HLA-DRB1 alleles proposed by Tezenas du Montcel and colleagues [ 11] regarding susceptibility to RA, across various Caucasoid and non-Caucasoid population samples, using publicly available data from the 13th IHWG RA studies.
An analysis of the decision trees built by J48 for different datasets revealed that, in datasets where both GO terms and PPI-related attributes are used, the latter tended to be chosen more often to label the root node of the trees, suggesting their greater relevance for the classification of DNA repair genes.
It should be noted that the top ranked features are not necessarily the ones that are individually most relevant to the classification performance since the relevance of features are evaluated in the context of other features, i.e., mutual information among features in terms of their collective discerning power are considered.
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