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However, numerous induced genes were found to be associated with more specific annotations of potential functional relevance (table 1 and supplementary data 3).
We have also found a statistical association between expression of the individual 3D-signature genes and tumor ER status, though small fold changes suggest this may be of limited biological relevance (Table 2).
Item 22 was retained for its clinical relevance (Table 1).
Gene Ontology analysis assigned biological processes to all epitypes, supporting their biological relevance (Table S2 ).
A total of 208 articles were retrieved and screened for relevance (Table 1).
Disruption of each of these pathways was assessed for prognostic or predictive relevance (Table 2).
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The provider panel of five physicians and five nurses confirmed all items that remained were moderately-to-highly relevant to this patient population, but also contributed several items that patients had not ranked as meeting the relevance threshold (Table 4). 1 Relevancy scores based on a scale of 0 4, where 0 indicated "not at all " relevant and 4 indicated "very much" (or highly) relevant.
We also enhance the method by extending the structure of the inverted list and adopting a relevance lookup table, which enables more accurate estimation of the relevance scores of candidate root nodes and efficient search of top-k answer trees.
We summarize the role of ANXA2 in tumors and its clinical relevance in Table 1.
First, unadjusted analyses were performed for baseline variables, chosen and categorised based on previous reports 5 6 8 and clinical relevance (see table 2).
The final GenoChip has over 130,000 highly informative autosomal and X-chromosomal markers, approximately 12,000 Y-chromosomal markers, and approximately 3,300 mtDNA markers without any known health, medical, or phenotypic relevance (supplementary table S2, Supplementary Material online).
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