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Given the high IDH clinical relevance, stratification according to IDH mutation should be taken into account for more effective future clinical trials [ 2, 16].
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This is of future clinical relevance for stratification of gastric cancer therapy.
Data generated from this validation study were also analysed for identification of SM and CN aberrations of potential clinical relevance for patient stratification or application of targeted therapeutics.
The assessment of adipokines and biomarkers of endothelial cell activation and MeS may be of potential relevance in the stratification of the CV risk of patients with AS.
Epigenomic aberrations in tumours of stage I and II patients without invasive tumour characteristics, however, may be associated with the development of aggressive tumours and have clinical relevance for risk stratification.
While the combustion product stream temperature was kept constant, its stoichiometry was varied independently from that of the reactant stream, leading to reactant-to-product stratification of relevance to practical combustion systems.
It also raises the important issue of the relevance of performing patient stratification at baseline during clinical trials.
Such findings reinforce the need for comprehensive health risk stratification and have relevance to the selection, prioritization, and cost-effective targeting of therapeutic lifestyle interventions for policy-makers and system-planners.
In this regard, addressing population stratification is of increasing relevance given the development of personalized medicine.
The macro-scale stratification demonstrates strong clinical relevance and reveals consistent risk tendency among cancer types.
Appropriate stratifications for stage and receipt of adjuvant trastuzumab were performed; a cutoff age of 50 years was also used as a stratification factor, although its relevance may not be as strong as the other two.
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