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For the sample weights, an increasing relevance should be given to those positions better covered by cell i and less covered by its neighbors in normal operation.
Therefore, they concluded that the generic (i.e., common to all treatments) transcriptional response to WOAs was minimal and suggested that more relevance should be given to the specific responses to the specific treatment conditions.
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Although pathogen identification may be regarded as a secondary feature of the test as it provides information of limited clinical relevance, particular attention should be given to avoid certain errors that may lead to inappropriate antimicrobial choice.
Prior to choosing a model for experimentation, thought should be given to relevance of cell type, genetic abnormalities, temporal-spatial regulation of expression of target genes, tumour microenvironment, and the metastatic potential of each model.
Further, in assessing the potential relevance of 2OG oxygenase inhibition by endogenous 2OG competitors, consideration should be given to the 2OG/inhibitor concentrations in cells, enzyme concentration, and 2OG KM/KD values; the latter can vary substantially (> 100-fold) [110].
Therefore, consideration should be given to all factors that have impact on the relevance of the test method and test results to a specific diagnostic interpretation or an epidemiologic situation.
There is thus a fundamental difference between the regulation of gene expression in germ cells and soma, as perhaps there should be given the germline's connectivity of generations that span millennia, versus the soma's single generation relevance.
Say prisoners should be given the vote.
They should be given the death penalty".
No timelines should be given.
As someone who grew up arguing that games should be given the same kind of consideration as books and films and the like, I find it a huge relief to see more people doing exactly that; this growing marketplace of opinions is what cultural relevance looks like.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com