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The relevance of selection analyses with codon models for downstream applications can be demonstrated on a selection of case studies.
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This may be of relevance for selection of patients for adjuvant treatment.
58 59 Thus, the potential criteria used in this DCE may not be the only criteria of clinical relevance for selection of individuals for surgery.
After presenting Darwin's own views on the evolution of the moral sense and the Victorian spectrum of opinion on the relevance of natural selection to morals, I argue that a consideration of human evolutionary history can be brought to bear meaningfully on a number of contemporary issues, including the nature of work and family relations.
These hypotheses raise the issue of the relevance of kin selection in the evolution of male social relationships in this population.
The relevance of our selection was supported by the fact that ribavirin, an already known influenza virus inhibitor, was identified with a negative enrichment of -0.83 and a pvalue of 0.00157.
While we cannot rule out more nuanced roles in brain evolution, the phenotypic relevance of positive selection on this locus is currently an outstanding issue.
The same approach may be followed as employed in ref. [ 13], [ 36] for demonstrating the relevance of sexual selection in promoting speciation in birds and insects, respectively.
To ensure the clinical and managerial relevance of study selection, meetings of the whole team will also be held at the beginning (first focus group) and middle (second focus group) of this process.
Similarly, the potential phenotypic relevance of this selection was extended from a role in the rapid expansion of human brain size [ 1- 3] to a more widespread, conserved role in primate brain evolution [ 7, 8].
Moreover, our cloning data also identifies a G at this point, but not a T, again suggesting the relevance of primer selection; nevertheless, all possible modulations are described in this early work (see Kosel 1994. [ 63]), yet it remains a primary reference for this lesion.
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