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p ∞ (i) is the final relevance of node i to recombination hotspots.
Let p0 be the initial vector showing the relevance of seeds to recombination hotspots (i.e., assigned by our prioritizing methods) and p t be a vector in which the i-th element shows the relevance of node i at step t.
Each of these p-values shows relevance of node i to individual members of the set K. As we want to identify the nodes that are statistically significant to at least one or more members of the experimental set, we define the "topological significance" score associated with node i as the minimum of the p ij values.
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RCR analysis was done to confirm the relevance of nodes already present in the literature model, and to uncover relevant nodes that were not identified during the construction of the literature model.
It is also useful for the theorem of Perron-Frobenius in linear algebra [6], which is one of the mathematical foundations for the page rank used to measure the relevance of nodes in a network.
Each ranking is based on the relevance of nodes for the network connectivity.
The second method (GA) presumes that relative centrality and the diversity of connections determine the relevance of a node: it relies on identifying the most prominent nodes within and across groups.
The presence and prognostic relevance of lymph node micrometastases in CRC patients without routine histopathological evidence of lymph node involvement by standard criteria is unclear.
The within-module relevance of a node is quantified through a standardized measure of the number of links the node devotes to its own community: z i = κ i − κ ¯ s i σ κ s i, (2).
On the basis of sensing relevancies, an energy efficient visual monitoring mechanism was presented by each source sensor [15], which would be a function of the monitoring relevance of the node for the application.
Recent data point to the relevance of lymph node dissection and reporting in thymic epithelial malignancy [ 19].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com