Sentence examples similar to relevance of binding from inspiring English sources

Biochemical studies could reveal that variations in post-translational glycosylation of constant regions in antibodies' heavy chains are also of high relevance for binding to different Fcγ receptors (44).

The relevance of VacA binding to these phosphatases was questioned because it is unclear if binding of VacA to RPTPα or RPTPβ has a significant impact on subsequent signalling or protein traffic [ 66].

van Rossum et al. [47] observed S1P binding to a putative TRPC3-PLCγ1 intermolecular domain that also interacts with phosphatidylinositol phosphates; the functional relevance of this binding is unknown.

However, the functional relevance of cholesterol binding to the receptor remains unexplored.

However, structural analysis of HU with ssDNA has been lacking, and the functional relevance of this binding remains elusive.

The relevance of peptide binding to erythrocytes is not to be diminished.

These results underscore the relevance of phospholipid binding and hydrophobicity to the chaperone-like activity of PDC-109.

The first novel aspect of the work presented here is the identification of the interaction between HLA-DRα2 and TIRC7, and the demonstration of functional relevance of this binding.

To validate the relevance of this binding, we tested residues in both the MHC-I CD and Nef that are of known importance for down-regulation in human cells.

In summary, this work provides novel data for the interaction between HLA-DR alpha 2 and TIRC7 and the functional relevance of this binding in lymphocytes in vitro and in vivo after immune activation.

In complement to these analyses, we also observed that the PDRE consensus was present in 11 out of 14 promoters of regulated genes from three different data sets (Figure S4) and thus highlights the relevance of this binding site for the regulation of these genes.