Sentence examples for relevance of activation from inspiring English sources

The mechanisms and relevance of activation of NADPH oxidase during seizure activity independent of chemoconvulsants is unclear, especially given the presence of alternative sources of ROS production.

Díez et al. [ 44] confirmed the relevance of activation of the TNF-α system in patients with hypothyroidism, showing that serum TNF-α and receptors of TNF-α were significantly higher than those detected in the control group.

These studies thus provide the groundwork for further investigations into the physiological relevance of activation of the integrative pathway and into the involvement of the ER-stress sensor BiP in the response.

In the context of TNFR1 signaling TRAF2-cIAP1/2 complexes are also of pivotal relevance for activation of the classical NF κB pathway and in addition prevent RIP1-mediated caspase-8 activation.

Detection of microglial distribution and activation by molecular imaging of the brain using positron emission tomography has underscored the relevance of microglial activation as a relevant biomarker of disease in multiple neurological and psychiatric conditions (Jacobs and Tavitian, 2012; Politis et al., 2012; Venneti et al., 2013).

The relevance of reductive activation of DOX by CPR for increasing cytotoxic activity of this drug towards sensitive human breast cell line MCF-7 has been also demonstrated using purified rat CPR (Bartoszek and Wolf, 1992).

Information on the functional relevance of this activation was obtained by using rTMS to induce temporary regional deactivations.

This study was designed to analyze the relevance of ventricular activation patterns for ventricular electrical remodeling after atrioventricular (AV) block in dogs.

Here, we investigate the relevance of this activation.

However, the mechanism and the clinical relevance of complement activation in human stroke remains unsettled.

To assess the relevance of ERK activation to muscle wasting, TB mice were treated with the MEK inhibitor PD98059 (PD) [16].