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A synthetic wastewater-based MMC exhibited the best observed BLASTN match of the PAO amplicons, raising concerns about the potential relevance in using synthetic substrates in the study of EBPR.
Relevance in using antibiofilm compounds is based on the restoration of antibiotic effectiveness by facilitating their penetration through compromised biofilm structure.
Similarly, relevance in using anti-QS compounds is based on the concomitant drastic reduction of virulence factors expression, which gives the necessary time for immune defense systems to elaborate appropriate responses by the recruitment of immune cells and production of specific antibodies.
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To reach the objectives of this work, we have used a procedure devoted to identify genes potentially related to FBN1 and tested their relevance in DS using publicly available DS microarrays datasets.
A few years ago, Heymann's group published the therapeutic relevance of using ZOL in the SRC model [6].
In an attempt to better simulate these in vivo events, some investigators have resorted to studying DC-T cell interaction in a collagen lattice [15], [16], but given that only a very small amount of collagen is actually available within the paracortical region of LN [17], where DC-T cell interaction takes place, the physiological relevance of using collagen in this context is questionable.
Furthermore, this study also provides useful insights into the environmental relevance of using laboratory strains in ecotoxicology when addressing the consequences of exposure to chemical pollutants on the fitness of wild populations.
The relevance of studies using in vitro cell lines is always of debate, especially in the epigenetic field, as microenvironment and culture conditions differ dramatically from in vivo conditions and can modify the chromatin profile of cells.
This also supports the relevance of using selective changes in the subtelomeric methylation as the biomarker of the disease.
The simulations show a certain relevance in the use of shell elements compared to solid elements despite their use restriction, and good correlation between the calculations and the tests.
We thus sought to confirm in vivo relevance using two approaches.
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