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Immunological markers (IgG4, CXCR5, CXCL13) can be of diagnostic relevance in specific settings.
Indeed, we found that small molecule targets have functional relevance in specific cancer pathogenesis.
R. rickettsii infection of A. dubitatum ticks in the 1 focus analyzed might indicate its relevance in specific epidemiologic scenarios.
With such systems at hand we could gain a better understanding of cancer dormancy and explore its relevance in specific clinical settings.
Group C is indicative of the involvement of immune function(s) and is associated with clinical relevance in specific (sub populations (selected markers such as NK-cell activity, which is associated with infection risk in athletes and elderly individuals).
Here we report that Galectin-3 (Gal-3), a β-galactoside-binding lectin involved in multiple biological functions that has already acquired diagnostic relevance in specific clinical settings, is variably expressed in most differentiated and less aggressive neuroblastic tumors, such as GN and ganglioneuroblastoma, as well as in a subset of NB cases.
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One paradox is that in order to confirm relevance, replications in specific populations must be undertaken.
However much of this information has yet to be compiled in the form that would allow using a molecule's chemical structure as an input to search for its potential relevance in a specific physiological, pathological or therapeutic area of interest.
We moved from the hypothesis that any kind of emotion might acquire social relevance in a specific context of interaction.
Hashizume et al. [ 39] used BLI to monitor tumor growth and pharmaceutical effect and found that BLI signal and tumor volume had a good relevance in this specific area and in animal model.
Overall these data, obtained in cell lines and primary culture, describe a so far unrecognized role for NOX4-derived ROS in activating redox-regulated intracellular pathways during influenza virus infection and highlight their relevance in controlling specific steps of viral replication in epithelial cells.
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