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Given that ex vivo purified primary T cells along with physiological ligands expressed in biological membranes are used and that individual cells in assay samples are interrogated by flow cytometry, this HTS system features superior physiological and therapeutic relevance, high sensitivity and statistical precision.
Sensitive windows during foetal development are still poorly characterised, making the relevance high and the confidence low.
Due to the high clinical relevance (high risk of blindness), a minor prevalence difference of predisposing external factors would be sufficient to declare clinical relevance for risk adjustment.
Due to its clinical relevance, high reproducibility, and FDA clearance, CellSearch ® can be considered as a benchmark for all other CTC detection methods appearing on the market.
Of further clinical relevance, high mRNA and/or protein levels of KLK4 7, KLK10 and KLK15 are associated with shorter progression-free and overall survival time of patients [ 87– 92].
Extracapsular spread was also predictive for both of these measures, as illustrated in Figure 4. Of the various multivariate models of OS and DFS, the one depicted in Tables 4-wrap> and 5-wrap> was chosen because of its clinical relevance, high statistical power, and high availability of patients and events.
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Coaching is known to improve student performance on tests with high personal relevance ("high-stakes tests").
Despite advertising, potential customers can't find what they want or are dumped on generic, low-relevance, high-bounce rate pages.
Of special relevance to high school and college students is cigarette smoking, including passive smoking, and alcohol consumption, especially binge drinking.
The clinical relevance of high chloride load and hyperchloremic acidosis remains, respectively, unclear.
The best business model is the one that is designed for customer relevance and high profitability.
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