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In medicine, therapy follows diagnosis and thus even if primaries are not found, the aforementioned biological notions have relevance for selecting a therapy for each patient.
The results of this study could certainly have clinical relevance for selecting the patients at risk of relapse in TNBCs, but subclassification of the lymphocytes constituting the tumor-associated immune system was not performed in their report.
We specifically tried to determine whether these markers could be of clinical relevance for selecting node-negative patients who could benefit, after the initial surgery, from more aggressive therapy.
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While the AOs being used in current clinical trials were largely selected through human myoblast cultures, the degree of relevance for each selected AO targeting many other dystrophin exons using such cell cultures to exon skipping in human in vivo remains to be determined.
Special volumes and issues of certain journals are of minor relevance for the selected paper sample.
Criteria for selecting questionnaires were: relevance to KOA, designed for self-administration, and together representing a wide variety of questionnaire types.
However, no specific strategies for selecting such high-relevance species of microorganisms have been offered, despite the large publicly available datasets of microbial genomes.
For these 676 results, abstracts were screened for relevance and selected for full text review.
We assessed the relevance of selected Canadian clinical guidelines on chronic diseases for patients with comorbidity and examined their quality.
These observations might have clinical relevance when selecting patients for HER2 targeted therapy.
As an example, knowledge of details of the portal anatomy and the surrounding tissues has proven to be of utmost relevance when selecting the model for the creation of intra-hepatic or extra-hepatic portosystemic connections.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com