Sentence examples for relevance concept from inspiring English sources

Communication of this population relevance concept could be aided by ecotoxicologists adopting the NOAEL from mammalian toxicology.

Hence, this research demonstrates and proves the clinical relevance, concept, and potential of this model-based approach to CVS monitoring and diagnosis.

To our knowledge, this study is a pioneering attempt at developing a relevance concept based systematic approach to reversely engineer the underlying genetic networks that describe the complex interplay of molecular elements that lead to complex diseases.

The aim of this study was thus to develop such a novel networking approach based on the relevance concept, which is ideal to reveal integrative effects of multiple genes in the underlying genetic circuit for complex diseases.

Furthermore, a correlation metric is commonly used for describing the relationships between genes, whereas the relevance concept can be used to characterize the target-dependent behaviour and properties of a feature gene, and thus is well suited to identify novel disease-relevant genes and to construct disease-specific gene networks.

Bell and Wang [ 6] have reviewed that relevance concepts have evolved considerably, from a simple and intuitive relevance concept for marginally filtering a feature to the sophisticated mathematical formalism of the concept that is quantitative and normalized, and which aims to capture the reality of biological complexities (epistasis or gene-gene interactions).

Recently, we introduced a disease-relevance concept, designed a novel relevance measure, and developed an ensemble decision approach for estimating the strength of (marginal) relevance of a putative gene related to complex diseases [ 5].

In some sense, the developed relevance-concept based networking approach was extended from our previously proposed algorithm [ 5] that aimed to identify disease relevance genes based on a marginal measure or best trees for classification.

In this study, we proposed and evaluated a novel relevance-concept metric (AFV) for identifying joint contributions to complex diseases based on genome-wide gene expression profiles, followed by constructing disease-specific gene networks.

In this study, we proposed and evaluated a novel relevance-concept metric (AFV) to assess the joint contributions of genes for complex diseases, followed by constructing disease-specific gene networks related to complex diseases.

These core concepts include ideas such as human agency, the relationship between social and individual levels of agency, concepts of causality, the relevance and concept of gender, to name just a few examples [ 71, 74].