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While cells that undergo cell death, due to apoptosis or other mechanisms, are of no further clinical relevance, cells or micrometastases that remain dormant are a possible source of later tumour formation and, therefore, recurrence.
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This proteolytic mechanism is of broad relevance for cell-cell communication, illustrating how distinct signaling pathways can be integrated into a single RIP module.
Several groups have questioned the clinical relevance of cell lines and cell line xenografts since tumors generated from immortalized lines may not perfectly represent the primary tumor 41– 41.
There, I set up a "biomechanics" lab to study the physical properties of bacterial cell surface polymers and their relevance to cell shape and continued to read about cell division and other subjects.
To investigate the potential preclinical relevance, K562 cells were transiently transfected with the siRNA targeting cyclin A2 by functionalized single wall carbon nanotubes.
Catalase is likely to be of particular relevance when cells are exposed to high H2O2 concentrations, due to its essentially non-saturable first-order kinetics.
Catalase is likely to be of particular relevance when cells are exposed to high H2O2 concentrations, on account of its essentially non-saturable first-order kinetics.
Pathways with expected biological relevance to cell cycle regulation, translation, cell structure and various signal transduction cascades are shown to be enriched.
The recent annotation of super/stretch enhancers in 86 human cell and tissue types further showcases their relevance to cell identity [ 28].
Formation is occurring by aggregate-aggregate collisions and, with a smaller relevance, single cell addition into the aggregates.
These results reveal the relevance of cell cycle control pathways in the cytotoxicity induced by the TK/GCV system identifying candidate genes as conditioners of TK/GCV sensitivity.
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