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The aim of the present study was to prepare sustained release pellets of aceclofenac using pelletization technique.
Therefore, further experimentations with slow release pellets are recommended.
Controlled release pellets were further coated with Eudragit L100 and RS100 to achieve pulsatile pellets (NMPP-1 to 5).
The delayed release pellets stored at 25 °C/60% RH were stable for a period of 10 mo.
Metoprolol succinate extended release tablets comprise a multiple unit system containing metoprolol succinate in a multitude of controlled release pellets.
The Enalapril Maleate (EM) pulsatile release pellets were prepared using extruding granulation, spheronization and fluid-bed coating technology.
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Polymethacrylate polymers are commonly used for the coating of prolonged-release pellets.
This study was designed to evaluate the in vitro release, pharmacokinetics (PK), pharmacodynamics (PD) and PK PD relationships of atenolol sustained-release pellets (AT-SRPs), compared with those of atenolol immediate-release pellets (AT-IRPs).
This paper put forward a deconvolution-based method for designing and optimizing tanshinone IIA sustained-release pellets (TA-SRPs) with improved efficacy in the treatment of variant angina.
The preparation of sustained-release pellets by melt pelletisation was investigated in a 10-l high shear mixer and ternary mixtures containing stearic acid as a melting binder, anhydrous lactose as a filler and theophylline as a model drug.
Study Design: Adult female Sprague-Dawley rats underwent oophorectomy at 9 weeks of age with concomitant placement of 21-day timed-release pellets containing either 17β-estradiol (n = 6) or progesterone (n = 6), or a combination of these (n = 6).
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