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Thus, hydrogels and lipid microtubules successfully provided the slow release of bioactive, compacted DNA.
It showed a prolonged, bi-phasic, release of bioactive BDNF, without burst effect.
We report the release of bioactive vascular endothelial growth factor (VEGF) from a mineralized, porous, degradable polymer scaffold.
Protein modifications occurring during sterilisation of infant formulas can affect protein digestibility and release of bioactive peptides.
Sustained release of bioactive naked siRNA and siRNA/TKO complexes were obtained for at least 28 days.
A sustained release of bioactive NGF in the low nanogram per day range was obtained for at least 15 days.
Care should therefore be shown when adopting this strategy to enhance release of bioactive agents from biomaterials.
Taken together, these findings suggest that this dual carrier is a versatile delivery system with potential for a spatiotemporally controlled release of bioactive molecules and cells.
Cellular automata and discrete iterations are used to model and simulate the release of bioactive agents (drugs) from bioerodible pellets used as controlled release devices.
The controlled presentation, patterning and release of bioactive molecules such as adhesion peptides and proteins on surfaces is important for the development of biomaterials that can guide cell behavior1.
We have developed a tailored peptide drug delivery system in which the viral capsid of P22 bacteriophage is modified to serve as a tunable nanocontainer for the packaging and controlled release of bioactive peptides.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com