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Compressive strength evolution was found to be related to the release of amorphous bulk phases, and in particular to the transfer of aluminium into the aluminosilicate gel, throughout the entire curing period of 90 days.
Solid dispersion systems in PHEMA hydrogels would be ideal for achieving immediate release of amorphous drugs as well as a modulated release through appropriate selection of polymer composition and particle size for release rate control.
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They found that their crystallization temperatures are lowered substantially due to the energy released by graphitization of amorphous carbon.
Verraedt, E., Pendela, M., Adams, E., Hoogmartens, J. & Martens, J. A. Controlled release of chlorhexidine from amorphous microporous silica.
The use of HPMC-AS in binary mixtures with DPD and GRI facilitated increased solubility and supersaturation at pH-controlled release of the preserved amorphous state of the dispersed drug, which even inverted the pH-dependent solubility profile of the weakly basic model drug (Dipyridamole).
To further illustrate the above described differences in drug release mechanism, Fig. 5 depicts the evolution of supersaturation of amorphous drugs released from crosslinked hydrogels versus that from water-soluble polymers.
The interpretation of the positive regression coefficients in this study revealed a strong correlation of sugar release with amorphous cellulose and hemicellulose.
The release of molecules adsorbed on the surfaces of amorphous carbon blacks has been studied using liquid-solid chromatography.
Evidently, that the continuous release of Zn 2+ from the amorphous oxide phase led to formation of more ZnO nanoparticles with increasing of calcination temperature.
This series of cellulose derivatives is designed for both adequate stabilization of amorphous drugs with high crystallization tendency, and timely release of those drugs.
Drug release profiles of a molecularly interacting amorphous celecoxib solid dispersion (ACSD) comprising of amorphous celecoxib (A-CLB), polyvinylpyrrolidone (PVP), and meglumine (7:2:1, w/w) were compared with crystalline CLB (C-CLB), in powder and capsule form.
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