Sentence examples for release from neurons from inspiring English sources

For example, 4-CIN (100 μmol/l) was used to preferentially inhibit neuronal MCT2 (Erlichman et al., 2008), but impairment of neuronal mitochondrial pyruvate transport and effects on lactate release from neurons were not assessed and ruled out.

Commonly found in both Clock mice models is an enhanced dopamine (DA) release from neurons in the VTA, which is reflected, for example, in an increased dopaminergic cell firing rate (Coque et al. 2011; McClung et al. 2005; Mukherjee et al. 2010; Roybal et al. 2007).

The latter finding indicates that glutamate production and release from neurons are enhanced, while normal postsynaptic signal transduction may be disrupted due to overexcitation by increased glutamate release.

Glutamate release from neurons evokes AMPA- and NMDA-receptor-mediated Ca2+ signaling, whereas ATP released by astrocytes also induces [Ca2+]i elevation via P2Y1 and P2X7 purine receptors in NG2 cells [5], [6].

This would be consistent with (i) data showing an increase in metabolic activity in glia upon increased glutamate release from neurons [42], and (ii) previously reported reduction of brain ATP levels in Mecp2-null mice [20] since ATP is also consumed in the synthesis of glutamine from glutamate [43].

Importantly, expression of TeTx but not IMP in the c346 pattern resulted in reduced ethanol-induced hyperactivity (Fig. 2F,G), indicating that evoked release from neurons in the c346 expression pattern regulated ethanol-induced hyperactivity, and suggesting that the dopaminergic PPM3 neurons may mediate this effect.

Thus, IPSCs arise due to conventional vesicular GABA release from neuron terminals, but SOCs are dependent upon an alternate GABA source that is non-synaptic and non-vesicular.

16 In addition, tPA and neuroserpin are rapidly released from neurons in response to neuronal depolarization.

Hence, we suggest that the toxic neurotransmitters that are released from neurons in the CNS function as tests of neuronal quality.

To assess neuronal viabilities in the presence of TLJN, the activity of LDH released from neurons was detected by LDH Assay Kit to test whether the cell viability was changed.

MSH peptides also can be released from neurons originating in the arcuate nucleus and other regions of the brain, where they act on pathways that control feeding and energy expenditure.