We propose a simplified approach that uses a phase transition equation coupled to the diffusion equation that describes the release rate of AIs from commercial CRFs in porous media; the parameters are as follows: a release coefficient, the solubility of the AI, and diffusion transport with decay.
Cycling of P was simulated as first-order uptake and release, with different uptake coefficients for open water/sparse submerged aquatic vegetation (SAV) areas (0.2 dand1) andenseSAVSareaseas (0.4 dand1), and a much lower, uniform release coefficient (1.97 × 10−4 day−10−4
Central composite design-response surface methodology was used to investigate the influence of factors, i.e., polyethylene oxide (Mw 1,000,000) content, NaCl content, iron powder content and weight gain, on the responses including ultimate cumulative release and correlation coefficient of drug release profile.
Table 1 shows the release parameters of PenG sustained release and adjusted coefficient of determination (R) values in various kinetic models tested.
The responses studied (Yi) were cumulative percentage released after 2 h (Q%2h), 6 h (Q%6h), 12 h (Q%12h) and regression coefficient of release data fitted to zero order equation (RSQzero), for Y1, Y2, Y3, and Y4, respectively.
The table indicates that the correlation coefficient of release data fits more into the Higuchi model for most number of cases than any other available models (using Millipore membrane and goat cornea as permeation medium).
Oxygen consumption tests were in good correlation with the results of insulin release assays, with a correlation coefficient of 0.82.
An in vitro release device was designed to mimic the in vivo release of Tα1, and good correlation was observed between the in vitro and in vivo releases, with the linear correlation coefficient of 0.9899.
In-cylinder pressure, net heat-release rate, A/F ratios, COV (coefficient of variations) of IMEP (indicated mean effective pressure), NOX, and smoke using the optimum condition factors are compared with those by original baseline diesel engine.
The interfacial properties such as debond strength, fracture energy release rate in Mode-II and coefficient of friction play important roles in determining the mechanical properties and strength of carbon/carbon (C/C) composites.
