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Residues of the αM2-cap show particularly large excursions in Keq while those in the cytoplasmic portion of αM2 show relatively smaller changes (Fig. 5B).
The presence of macroscopic observable changes that are computable from a large number of relatively smaller changes mean that it may be possible to find an objective mathematical formalism to infer the turning point at which these radical changes occur.
The further accumulation of molecule depth larger than 100X led to relatively smaller changes of map number and N50 length.
A self-controlled study design was used to overcome the problems of larger between-individual variation interferences with observations of relatively smaller changes caused by environmental exposure.
This was accompanied by relatively smaller changes in its expression at 3, 8 and 24 h after loading (1.6-, − 1.3- and 1.5-fold, respectively).
Furthermore, when considering the magnitude necessary for a change to be considered important, larger changes may be required at the individual level, whereas relatively smaller changes may be interpreted as clinically important when considered at the group level [ 23, 24].
Similar(52)
Meanwhile, relatively small changes can meet fierce resistance.
Over a period that long, relatively small changes in the present can have huge effects.
The authors stress, however, that relatively small changes could bring significant effects.
His zero-based spending review identified savings of £2bn but many were relatively small changes.
All these costs can vary considerably with relatively small changes in the strategy selected.
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