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Five approved projects have gone out of business, a relatively low failure rate, she said.
In AC, however, RCTs are difficult to perform because of its low incidence and a relatively low failure rate.
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The relatively low failure rates (∼20%) in the MAESTRAL study suggest that treatment with broader spectrum drugs, such as moxifloxacin or amoxicillin/clavulanic acid, is appropriate in this group of patients with moderate-to-severe AECOPD managed outside the hospital.
In a classic Catch-22, a low failure rate makes failures more likely.
"The production line has to run efficiently and deliver a very low failure rate.
The Japanese, however, have achieved low failure rates even with relatively broad product lines and rapidly changing designs.
All failures were treated with revision reconstructions.We found low failure rates in both groups.
EvaGreen gave most robust result and lowest failure rate [ 37].
This study has small numbers due to the relatively low rate of failure following two-stage revision for PJI and therefore was not powered to detect small effects.
Additionally, the results illustrated that AE technology could reflect the initial fracture moment and final structure failure at a relatively low loading rate, and consequently could acquire the initial and failure fracture loadings.
Incomplete eradication of these clones is the main cause of treatment failure demonstrated as a relatively low CR rate and a high early relapse rate of more than 50%%, unless treated by allogeneic hematopoietic stem cell transplantation (HSCT).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com