Whilst the clinical arguments (lower risk of dilution errors) supporting Aprokam over PFS are unequivocal, there remains some reluctance among budget-holders to adopt the licensed product available after consideration of the relatively higher acquisition costs associated with Aprokam.
Another force driving the lack of utilization of MS-based methods is the relatively high capital acquisition costs of a MS, costs of training personnel to operate the analyzers, and the relatively low test throughput compared to automated chemistry analyzers.
Picture Archiving and Communication Systems (PACSs) can be relatively high cost acquisitions if the intended purpose of use is limited to educational and research use.
This enabled us to define a line that passed through large numbers of neurons with relatively high temporal resolution (acquisition rate of 50 100 Hz).
Health beliefs and practices that were instilled in their countries of origin appear to be maintained even after living in the United States, as the relatively high frequency of acquisition of nonprescription antimicrobial drugs in the United States demonstrates.
In Europe, we observed a relatively high risk for MRSA acquisition in travelers to the United Kingdom, Ireland, and southern Europe, which is consistent with the high prevalence of MRSA reported for these regions (26 – 26 ).
That does not mean they are not good business models – with subscription businesses, the upfront investment in customer acquisition is relatively high, but the return from the customer takes a little bit longer than the old software licensing model (lifetime value is spread across the life of contract with SaaS, not upfront).
For DrotAA, the relatively high drug costs - the acquisition cost of a 96-hour infusion is around £5,900 (2010 prices) - and associated critical care stay and the tradeoff between potential benefit and risk mean that rigorous CEA is particularly important.
Conversely, low LDMC and large leaf areas at higher elevations may be indicative of fast resource acquisition and relatively high productivity, even in areas where growing seasons are short and unpredictable (Kudo et al. 1999).
