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We conclude that a single nucleotide deletion transformed the ancestral paleoAP3 motif into the euAP3 motif with relatively few associated nucleotide changes.
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However, psychiatric disease GWAS studies have revealed relatively few robustly associated and replicated loci [2], [3], perhaps attesting to the more complex heterogeneity underlying psychiatric disease phenotypes.
Unfortunately, an evidence-based review identified relatively few predictors associated with clinically significant changes in the probability of weaning success or failure [ 2].
This study focused on relatively few genetic variants associated with defined biochemical alterations.
Post-hoc contrasts across the groups (FDR p-value < 0.05) revealed relatively few transcripts were associated with dominance status.
While the false negative rate may mean that many duplicate pairs were not detected, the general trend indicates that most genes tend to have relatively few redundant genes associated with them.
The 5 dpa time point captured many transcriptional responses that are induced by injury and/or amputation but relatively few that are associated with known or suspected neurotrophic signaling pathways.
CGRP may be the more suitable for clinical use because of its short half life, its capability to achieve controlled hypotension and the relatively few side effects associated with its use.
However, there have been relatively few clinical reports associating Na+ channel abnormalities with DCM, most strikingly observed in 13-year-old proband, and all of these have consistently resulted in loss- rather than gain-of- function.
Visual examination of both hypoxic and AAV-HIMF-treated lung sections revealed GFP+ cells associated with the vasculature; in comparison, relatively few GFP+ cells were associated with the pulmonary vasculature of normoxic or AAV-null treated mice (Figure 2A D).
In contrast to PC1, the biological interpretation of the PC2 and PC3 axes is more complex given the large number of genes expressed, the low factor loadings associated with the majority of these genes and the fact that relatively few genes are strongly associated with PC2 and/or PC3.
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