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Furthermore, the relative requirement for NELF is dictated by attributes of the flanking cis-regulatory information.
Interestingly, the relative requirement for NELF depends on attributes of the flanking cis-regulatory information.
Taken together these observations suggest that the relative requirement for NELF depends on interactions involving these flanking cis-regulatory DNA regions and NELF-associated paused Pol II complexes.
The differential effect of NELF-E depletion on expression of the different slp1-lacZ reporters further indicates that the relative requirement for NELF is a function of the extent of flanking cis-regulatory information.
In this model the relative requirement for NELF in allowing for active transcription would depend on the strength of the interaction between a promoter and an enhancer and the relative efficiency of generating productive elongation complexes.
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A barcode count reflects the abundance of the corresponding strain at the end of the experiment, that is, a quantification of the relative requirement of the deleted gene for growth in the tested condition.
The results in Fig. 6 permit an interpretation of the relative energetic requirements for formation of different groups of interacting proteins.
(DOE-NETL 2007b) In another study, the U.S. DOE compared the relative water requirements for new pulverized coal and IGCC plants with and without carbon capture (DOE-NETL 2007c) using the cost and performance impacts associated with CCS technologies on coal-based power plants (DOE-NETL 2007b) (Fig. 6).
Therefore, Muggli proposed to estimate the dietary vitamin E requirement by taking the relative vitamin E requirement for individual PUFA into account.
While BCR-ABL, TEL-PDGFRB and TEL-JAK2 activate overlapping signaling pathways, the relative contribution and requirement for these pathways downstream of each fusion is not clear.
The management of salivary gland carcinomas can be confusing due to the extreme diversity of tumor types, their relative rarity, the requirement for long-term follow-up, and strategy for treatment in many instances to predict outcome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com