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Indeed, our neuropathological study has shown that CMIs are present predominantly in the arterial borderzone between the middle and posterior cerebral artery territories in AD patients [ 33], which may coincide with the relative predilection of CAA pathology in posterior brain regions [ 42].
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Changes in MRI signals show that in situ uptake of free particles has predilection to tumor cells relative to normal bladder epithelium.
These studies involved Japanese patients, where there is a predilection for distal gastric cancer and relative lack of gastro-oesophageal junction tumours.
A predilection to over-express MDMX at higher relative levels was noted in all these cases and all also had positive P53 expression.
In contrast, the distribution of FUS pathology in late-onset BIBD cases demonstrated a predilection for pyramidal and extrapyramidal motor regions with relative sparing of cerebral cortex and limbic regions.
Notably, this effect was not only due to the predilection for frontal and temporal cortex or due to the relative sparing of the visual cortex.
MAP like many autoinflammatory conditions is a targeted organ and site specific disease exhibiting a peculiar and distinctive predilection to involve select small arteries and arterioles of the subserosa with relative sparing of the microvasculature of the lamina propria.
The reason for the predilection of CD80 for lethality and CD86 for protection may lie in their relative affinities and binding kinetics for their ligands, CD28 and CTLA4, with CD80 having a relative higher affinity for CTLA4 [28], [29], [30], [30].
Cell loss was non-uniform, showing a clear predilection for dorsolateral (motor) striatum, and a rostro-caudal gradient of cell loss, with relative sparing of caudal regions.
Traditional bone involvement, such as osteoitis fibrosa, has become very rare (< 1%) in primary hyperparathyroidism (PHPT); nevertheless, fractures seem more frequent than in controls, with a predilection for fractures of the distal extremity of the radius, pelvis, ribs and vertebrae, and a relative modest incidence of fractures of the upper extremity of the femur.
The traditional bone involvement like the osteoitis fibrosa has become very rare (<1%) in primary hyperparathyroidism (PHPT), nevertheless, fractures seem more frequent than in control with a predilection for the fractures of the distal extremity of the radius, pelvis, ribs and vertebrae, and a relative modest incidence of fractures of the upper extremity of the femur.
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