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The relative intervention effects could therefore be underestimated by our results.
Even so, exposure times varied among intervention conditions: these are often difficult to balance with behavioral interventions and may contribute to relative intervention effects.
Otherwise, the random-effects approach provides wider confidence intervals (CIs) for the relative intervention effect and is thus considered more clinically conservative.
The trial protocol also pre-specified comparisons of relative intervention effects for subgroups based on education and the presence of the Apo-E allele.
From these, we projected the sample size required for 90% statistical power to detect differences in a mean relative intervention across follow-up in a two-armed trial (two-sided, unadjusted significance level of 0.05) from a repeated measures model.
With indirect and MTC comparisons in their infancy, it is not surprising that there has been little comparison between the influence of the different approaches on the estimation of relative intervention effects.
Similar(53)
Contraindications are: absolute (internal bleeding in progress, recent spontaneous intracranial hemorrhage) and relative (interventions Chir. <10 days, stroke <2m., Gastric bleeding <10 days, Major trauma <15 days, Recent CPR, PTL <100,000, poorly controlled severe hypertension, pregnancy).
Examine how the identified cancer patients' and first degree relatives' socio-demographic characteristics, disease characteristics (for index case), risk category (for first degree relatives), intervention groups and providers' characteristics influence whether or not: a) colorectal cancer patients; and b) first degree relatives of colorectal cancer patients, are appropriately screened.
Furthermore, control conditions that include active interventions could underestimate the effect of some interventions relative to no intervention.
If the discount rate applied to future financial costs and benefits is also applied to future health benefits, preventive interventions are disvalued relative to interventions whose health benefits occur in the present (Schwappach 2007).
Control respondents were less likely to report hospital or health centers as places to test for HIV relative to intervention respondents (26% vs. 41%).
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