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The more homogeneous the proton beam dose distribution in a film is, the lower the relative dose variation.
Median relative dose intensity was 85% for both docetaxel and vinorelbine.
(a) Relative dose variation as measured across the proton beam recorded using RCF films (as done in ref.61), for various target thicknesses.
Response was associated with good performance status (PS) but not with primary site, site of recurrence, histology, prior irradiation, or relative dose intensity.
Primary outcome measures included anemia, thrombocytopenia, severe neutropenia, febrile neutropenia, and both planned and actual relative dose intensity (RDI).
Figure 3 shows the relative dose rates between pairs of locations.
The relative dose intensities for S-1 and cisplatin were 48.4 and 74.1%.
End points included reductions in dose intensity, delivered relative dose intensity (RDI) <85%, and the incidence of chemotherapy dose delays >/=7 days and dose reduction >/=15%.
This means that for every 100 litres of water that a fish passes through its body, it will ingest one relative dose.
The median relative dose intensity was 93.5%.
Overall mean relative dose intensity was 84%.
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