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Others focus on providing defined periods during which medications are discontinued in order to achieve a period of relative alertness, thus reducing the likelihood of drug accumulation and providing additional opportunities for ventilator weaning [ 28, 29, 31].
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Moreover, objective alertness was enhanced in NB relative to NS and NN, which showed the larger P300 amplitude after nap.
18 Individuals with high scores on morningness have their peak of alertness earlier in the day relative to individuals with low scores.
Attention revolves around alertness (the ability to become alert and focus on a task) and vigilance (sustained alertness).
Such energy regulation of GABAA receptor function could contribute for example to the well-known heightening of alertness by hunger in contrast to the relative lethargy induced by satiety: hunger cuts down ATP supply, thereby inducing GABA-current rundown and decreasing inhibitory CNS neurotransmissions mediated by long β2 isoform-containing GABAA receptors.
To detect changes in central alertness alpha and beta activity changes in the relative band power and absolute band power of the occipital and central electrodes (P4O2, P3O1 and F4C4, F3C3, respectively) were used, and also changes in peak frequency in the occipital region [ 13].
Across groups, alertness ratings were significantly higher for speech and music relative to their scrambled versions (Bonferroni-corrected pairwise Wilcoxon sign-rank comparisons all P < 0.05, no other comparisons significant).
The relative band power of the beta activity in P4O2 increased significantly (P = 0.017), indicating a higher state of alertness.
The ANOVA revealed a significant effect of the work episode on subjective alertness (F2,101 = 67.8; p<0.001); planned comparisons (t-tests) indicated that alertness levels were lower during night work relative to day work (day: 71.3+3.8 vs. night: 52.3+3.2; p<.001) and that it was lowest on the first night shift (night 1: 39±4.05 vs. subsequent nights: 52.3±4.05; p<.052.3±4.05
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