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The Ontology of Clinical Research (OCRe) is an OWL 2 model of the entities and relationships of study design protocols for the purpose of computationally supporting the design and analysis of human studies.
They are divided into descriptive studies, mainly providing information that characterizes an individual or population, and analytic studies, which are primarily aimed at answering questions about the relationships of study participant characteristics and disease outcomes.
The relationships of study drug lipophilicity and protein binding with circuit drug concentrations are summarised in Table 1 and Figure 2.
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Comparisons with the non-atopic group should provide valuable insights into the relationship of study findings to the general population.
In addition to RCTs, less robust NRCT and UCT designs were included in this review to exhaustively review the existing literature, the relationship of study quality to outcomes achieved, and identify gaps in the literature.
Finally, we also performed independent contrasts for taking into account the evolutionary relationships of our study taxa.
Genetic relationships of the studied populations were firstly depicted by phylogenetic reconstructions.
The relationships of the studied taxa revealed by the Bayesian analysis are similar to those reported by Hoffmann et al. [ 22].
Multiple linear regression analysis was performed to determine the independent relationships of the studied variables, and standardized β was represented as the coefficient β.
Table 3 shows AEs occurring in ≥10% of patients in either treatment group, regardless of relationship to study drug.
Toxicity was recorded by worse grades experienced regardless of relationship to study drugs.
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