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Such models can be useful in establishing pharmacokinetic‐pharmacodynamic relationships, exploring optimal dosing regimens, and predicting clinical results based on preclinical studies.
Some of the advocacy strategies undertaken by the Centre were deliberate, and following much reflection, and at other times they were about 'right timing' and seizing opportunities as they arose, taking intuitive decisions, networking through informal contacts and personal relationships, exploring innovative ways to push the boundaries on sexuality.
Given that half of the terminal cancer patients in Japan will remain uninformed until death and that more time seems to be required for patient disclosure to be widely accepted in Japanese culture owing to its unique family-individual relationships, exploring appropriate terminal care services for uninformed patients is an urgent need in Japan.
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As the literature has moved towards more detailed exploration of possible mechanisms underlying the relationships explored, we follow that direction in our mediation analysis.
As our understanding of identity and inequality becomes more complex, it is stimulating to see the dynamics of human relationships explored in different ways.
The role of art and the work of the artist are firmly positioned at the core of many of the relationships explored.
Figure 1 summarizes the relationships explored in this research.
Current trials are ongoing (NCT02138890 and NCT02262364) to collect data which can be used to further examine the relationships explored in this manuscript.
We chose them, knowing that these were the worlds in which we could learn and forge new relationships, explore our passions, and find out who we truly are.
Hence, prospective, longitudinal studies are needed to establish the precise nature and the directions of the relationships explored in this study.
Figure 2 summarises the relationships explored.
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