Although analyses based on morphological and combined data supported this relationship, sequences of the Rbp3 gene alone instead placed Oryzomys among a group that included Nectomys, Sigmodontomys, and a few other genera.
Protein functional annotation relies on the identification of accurate relationships, sequence divergence being a key factor.
To examine LINE-1 relationships, sequences from the 3' region of the reverse transcriptase from 21 species (representing 13 orders across Afrotheria, Xenarthra, Supraprimates and Laurasiatheria) were obtained from whole genome sequence assemblies, or by PCR with degenerate primers.
Moreover, we propose a conceptual framework that allows us to quantify the relationship between sequence, structure, and binding energetics.
Enzymes are therefore an ideal functional group to study the relationship between sequence expansion, functional divergence and phenotypic changes.
We determine the relationship between sequence divergence and Bayesian phylogenetic reconstruction ability using both natural and simulated datasets.
Taken together, these observations show that the relationship between sequence, structure, and function is complex.
Lord and colleagues introduced the use of semantic similarity to investigate the relationship between sequence and annotation [15], [16].
Through the statistical modeling process we shed light on the variability in the relationship between sequence similarity and function similarity.
We further evaluated the relationship between sequence depth and rate of known events and racall values.
