The observation concerning "functional polymorphism without speciation" is interesting, but it is not clear why it is buried in an additional file.
In order to determine the relationship between functional polymorphisms of FCGR and possible arthritogenic anti-GPI antibodies in human conditions, we examined the correlation of these polymorphisms with anti-GPI positivity.
Therefore, none of the two effects has a clear relationship to known functional polymorphisms or to IRF5 function.
To address these limitations, we investigated the relationship between APOE functional polymorphisms and age at onset of ALS in a large set of 508 families.
In particular, this relationship concerns the degree to which access to utilities in the environment is facilitated or obstructed, depending on the functional capacity of individuals.
The relationship between cognition and a functional polymorphism in the catechol-O-methlytransferase (COMT) gene, val108/158met, is one of debate in the literature.
This study suggested that a relationship existed between a common functional polymorphism (Val 108/158 Met) in the Catechol-O-methyltransferase (COMT) gene and schizophrenia [ 39].
Indeed, our study underscores how much remains to be discovered concerning the role of functional polymorphisms in cognitive function and the need for further research in order to fine-tune useful clinical intermediate phenotypes that affect high-level information processing.
However, the relationship between these two functional polymorphisms and nasopharyngeal carcinoma (NPC) susceptibility has not been explored.
Similar to traditional QTL mapping, genome-wide association mapping relies on the strength of linkage disequilibrium (LD) across a diverse population, and aims to identify relationships between markers and functional polymorphisms that determine traits of agronomic, aesthetic, and evolutionary interest.
A functional polymorphism of COMT, Val108/158 Met, affects prefrontal function, and the high-activity Val allele has been reported to be a genetic risk factor for schizophrenia.
