The main aim of this study was to investigate the relationship between 3 functional polymorphisms in the regulatory regions of the human gelatinases MMP2 and MMP9 and the human stromelysin MMP3 and lung cancer risk in the individuals from the CAPUA study.
To address these limitations, we investigated the relationship between APOE functional polymorphisms and age at onset of ALS in a large set of 508 families.
The aim of this study was to investigate the relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the presence of obesity and metabolic risk factors.
In order to determine the relationship between functional polymorphisms of FCGR and possible arthritogenic anti-GPI antibodies in human conditions, we examined the correlation of these polymorphisms with anti-GPI positivity.
To explore the relationship between functional polymorphisms in FcγRs FCGR3A-158V/F FCGR3A-158V/F31H/R) and FCGR2A-131H/R FCGR2A-131H/Rsitive for andi-GPI arthritiss, we evaluated these indindividualsth respositiveforR genotype.
Based on the fact that gene polymorphisms related to energetic expenditure and adipogenesis can be associated with obesogenic phenotypes in different populations, this study focused on the possible relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the accumulation and distribution of body fat and metabolic profile.
However, the relationship between these two functional polymorphisms and nasopharyngeal carcinoma (NPC) susceptibility has not been explored.
Therefore, none of the two effects has a clear relationship to known functional polymorphisms or to IRF5 function.
The relationship between cognition and a functional polymorphism in the catechol-O-methlytransferase (COMT) gene, val108/158met, is one of debate in the literature.
Similar to traditional QTL mapping, genome-wide association mapping relies on the strength of linkage disequilibrium (LD) across a diverse population, and aims to identify relationships between markers and functional polymorphisms that determine traits of agronomic, aesthetic, and evolutionary interest.
This study suggested that a relationship existed between a common functional polymorphism (Val 108/158 Met) in the Catechol-O-methyltransferase (COMT) gene and schizophrenia [ 39].
