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We then analyzed the miRNA expression profile in relation with the expression of lipogenic key-factor.
We here provide an analysis of the epiplasmin family on the presence of putative TATA-like elements and upstream sequence elements (USE) in relation with the expression levels of the corresponding gene products.
Therefore, as changes in the expression of p53 were not evident in relation with the expression of RAC3, we could speculate that p21 inhibition by RAC3 overexpression could be a possible mechanism affecting telomerase activity, independent of p53.
The codon usage bias and the 3′ codon context bias showed a clear direct relation with the expression levels and GC% of the ORFs, but not the sequence length.
NF-κB, the transcription factor that has a reciprocal relation with the expression of the IL-8 gene and its protein product [ 25, 28, 29], was diffusely and strongly positive in the HSC-3 cells and less so in the myoma and other stromal cells.
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With respect to their relation with cancer, the expression levels of some CKs, such as CK19, are abundant and stable among tumours, therefore these molecules are considered useful markers for micrometastases or speculation on occult primary cancer (Fujita et al, 2006; Liu et al, 2008).
Since there were reports that implied the role played by PLK1 in pancreatic cancer and indicated the PLK1 can be targeted by miRNA [ 11, 14], we first checked the expression level of mir3686 and its relation with the PLK1 expression in a pancreatic carcinoma derived cell line PANC1 cell.
A recent study [ 27] reported that the surface expression of α4β7 integrin is regulated in a homeostatic relation with the surface expression of α4β1 integrin on T-cells since high expression of α4β1 integrin resulted in a loss of α4β7 integrin.
Of note, expression levels of c-met exhibited an inverse relation, with the highest expression in MDA-MB231 cells.
In other words, in both species, the exon size has approximately 1.7 times stronger relations with the gene expression level than with the gene expression breadth.
From the ratios of coefficients (Tables 2 and 3), we can conclude that the intron length has approximately 1.8 2.0 times stronger relations with the gene expression level than with the gene expression breadth.
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