Sentence examples for relation of dose from inspiring English sources

The primary endpoints of the study in patients with prostate cancer were to document physical targeting of BMTP-11 and to evaluate the relation of dose to toxicity and efficacy in humans that would support a full phase 1 trial.

To the best of our knowledge, this is the first meta-analysis to examine the exposure-response relation of dose of iron, duration of use, and haemoglobin concentration on birth weight and risk of low birth weight and preterm birth.

Objectives To summarise evidence on the associations of maternal anaemia and prenatal iron use with maternal haematological and adverse pregnancy outcomes; and to evaluate potential exposure-response relations of dose of iron, duration of use, and haemoglobin concentration in prenatal period with pregnancy outcomes.

Our primary aim was to determine the degree of platelet aspirin responsiveness in patients, as measured by commonly used methods, and to study the relation of aspirin dose to platelet inhibition.

The pharmacokinetics [area under the curve (AUC), Cmax and time to reach Cmax (tmax)] and the safety and tolerability profiles of lesogaberan in relation to dose were also assessed as part of the secondary objectives of the study, as was the relationship between the pharmacokinetics and pharmacodynamics of lesogaberan.

Characterization of plasma effects in relation to doses of these secretase inhibitors can help to predict central nervous system (CNS) effects as clinical trials enter phase 2 or 3. Unfortunately, plasma biomarkers are not available for most non-Aβ mechanisms of action.

4. Conduct case control studies for analyses of late mortality and morbidity and their relation to dose and planning of different chemotherapy agents, targeted therapy, hormonal treatment and radiotherapy.

This begs the question of whether it is critical to adjust for tobacco and alcohol consumption in evaluating relations of lead dose with cardiovascular and cognitive outcomes.

Furthermore, to the best of our knowledge, no systematic evaluation has been done of exposure-response relations of iron dose and haemoglobin concentration in the prenatal period with adverse birth outcomes, identification of which would prove critical to the efforts to reduce this burden.

The relation of duration and dose of statin therapy to clinical outcomes in COPD or anti-inflammatory effects is unclear.

But here neither a relation of experimental irradiation dose and model toxicity parameters nor a clear matching of model compartments and CFU-S exists, so our results can only be interpreted in a qualitative way.