Point five on DeCarolis best practice checklist addresses applicability and re-usability which is discussed related to utilisation.
They are generally demographic factors that are related to utilisation and are not easily altered.
Both these aspects were related to utilisation through the cost of dental treatment or the fear of the cost of dental treatment.
Symptoms for which there is no evident medical explanation pose a special challenge to the health care system in general, to GPs in particular, as well as to society as a whole due to costs related to utilisation of health care and welfare resources[ 2- 4].
We conducted a rapid evidence synthesis in two stages: First, we searched databases, such as the Cochrane Database of Systematic Reviews (CDSR) and Database of Abstracts of Reviews of Effects (DARE), for systematic reviews of interventions that reported outcomes related to utilisation of generic drugs.
Systematic reviews, HTA reports and overviews were included if they evaluated the effectiveness or efficacy of an intervention and reported an outcome or outcomes related to utilisation (prescribing or dispensing) of generic drugs regardless of the indication, setting or type of healthcare system.
Data relating to resource utilisation associated with progression and second line therapy were collected via a retrospective case note review.
Reviews that were restricted to clinical outcomes, psychosocial outcomes, acceptability, cost-effectiveness or feasibility were excluded from this overview, unless data relating to healthcare utilisation could be extracted.
Interviews included information about socio-demographic characteristics, perceptions about risks in pregnancy, behaviour relating to pregnancy, utilisation of health facilities during pregnancy and childbirth, and factors that led to home deliveries (see Additional file 2).
Data relating to resource utilisation associated with progression and further chemotherapy were derived from a retrospective case note review for 62 patients in centres in France and the UK who had progressed during the study.
