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This allows scientists and engineers to experimentally test their hypotheses relating sequence to function.
The prediction and design approaches deal with reverse problems of relating sequence and structure, but share the main computational principles, visual representations and modeling approaches.
The increasing amount of information stored in publicly available biological data bases is retrieved to find approximate solutions relating sequence to protein structure.
Our analyses confirm some previously detected trends relating sequence divergence to structural variation but for a much larger dataset and in some superfamilies the new data reveal exceptional structural variation.
Despite the relative difficulty of predicting measured in vivo protein binding sites from DNA sequence, and relating in vivo TF binding sites to the effects of perturbing the same TFs, relating sequence elements directly to expression patterns (and vice versa) has been remarkably productive in yeast.
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Additional data relating sequences and their recognition by plasma samples should confirm whether antigenic sequences vary geographically.
Major histocompatibility complex class I polypeptide-related sequence A (MICA) is a prototypical NKG2D ligand.
Sequencing of a polyploid-specific band (absent in both parents) revealed a microsatellite related sequence.
This score was unable to discriminate related sequence pairs.
Although structurally related, sequence related and mechanistically related, their biochemistry showed that they catalyzed four different reactions [ 23].
The next most closely related sequence of gltA, with 96% similarity, was R. felis.
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