Sentence examples for related template from inspiring English sources

Although producing accurate models remains a challenge when only distantly related template structures are available, it has been suggested that sequence alignment is the bottleneck in this process, as quite accurate models can be produced if a "perfect" sequence alignment is known.

Consensus sequences were attained using a complete published sequence as a template or, where a closely related template was not available, a de novo assembly.

To go beyond the limitations of current alignment methods, this article presents a novel Conditional Neural Field (CNF) (Peng et al., 2009) method for protein threading, called CNFpred, which can align a sequence to a distantly related template much more accurately.

Recruitment posters and related templates can be requested.

Modeling GPCRs, including Tas2rs, proved successful in many cases14,15,16, but remains challenging, especially when closely related templates are lacking17.

Within liposome 'protocells' RNAzyme replicases would copy neighboring (related) templates using RNA ligase and/ or polymerase activities.

With this new list, we were able to apply protein related templates such as 'Protein(s) → Protein Domains'.

The effective combination of multiple algorithms considerably extends the coverage of target sequences by distantly related templates and increases the overall modeling accuracy.

CNFpred performs especially well when only distantly related templates are available or when the proteins under consideration have sparse sequence profiles.

The structural alignment step allows very distantly related templates to be recognized, while the use of profile profile sequence comparison highlights the residue pairs that are mutually conserved.

The pharmacology of the heterocyclic moiety alone and peptides AMW3-130 AMW610were were also included for pharmacological comparisons of the different but related templates.