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Glucoamylases are inverting exo-acting starch hydrolases releasing β-glucose from the non-reducing ends of starch and related substrates.
These different effects suggest preferred structural and functional microbial responses to anticipated contaminants may potentially be engineered by controlled pre-exposure to the same or closely related substrates.
Within the Faure Sill complex (Shark Bay, Western Australia), a combination of remote sensing analysis, seismic stratigraphy and cores to ground truth, together with radiocarbon dating, demonstrate the interconnection between sediment body morphologies, seagrass related substrates and pre-existing topography and reveal the system as a channel bank complex.
Guided by the structural homology, we show that UlaG is able to cleave phosphodiester linkages in cyclic nucleotides, suggesting that the conservation of the fold and of the key catalytic residues allows for the evolutionary acquisition of substrate specificity for novel but related substrates.
Such a family could provide in planta an enzymatic reduction of progesterone and related substrates.
The recombinant P5ßR protein was investigated for catalytic activity with several related substrates.
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Within the entire 102-peptide panel, 23 angiogenesis-related substrates were identified (Fig. 3), and sunitinib inhibition of these phosphosubstrates was stronger in patients with negative DTC status than in DTC-positive patients (P = 0.019; Supplementary Fig. 3).
Based on this finding, it is reasonable to speculate that PGRN has a lysosomal function related to turnover of lipofuscin-related substrates.
These changes were directly related to the inhibition of Furin-mediated activation of several cancer-related substrates [22], [28].
Comparative analysis of energy recovery from anaerobic digestion using vinasse-related substrates indicates that the production of methane has a higher energy yield than production of hydrogen.
Wild-type TMOs were initially evaluated for their ability to oxidise PEA and structurally-related substrates, providing better understanding of the factors responsible for controlling the regiospecificity.
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