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All patients had no related malformations in other parts of the body.
Recent work on chromosomal anomalies in EA/TEF suggests that there are other haploinsufficient susceptibility loci for these and related malformations, notably at 13q and 17q, and quite naturally as a result of clinical studies, our knowledge will grow.
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The relationship between the estrogenicity of α fractions (TEXB-α) and the variables most frequently related to malformations was investigated.
Preconception care is effective in reducing diabetes related congenital malformations, preterm delivery and maternal hyperglycemia in the first trimester of pregnancy.
These models show DS-related phenotypes including cognitive and behavioral impairments, and craniofacial and cardiovascular malformations related to DS phenotypes, although their intensity was not related to the length of the Ts region (9– 17, 17– 23).
While chromosomal translocations are usually associated with a normal phenotype, they can still cause male infertility as well as recurrent miscarriages and fetal malformations related to their transmission in an unbalanced state.
We found an increased risk for male urogenital malformations related to the combined effect of environmental estrogens in placenta.
Vinclozolin has been identified as an anti-androgenic endocrine disruptor that produces malformations related to androgen inhibition in rats [ 1].
Fetal akinesia deformation sequence (FADS) refers to a clinically and genetically heterogeneous group of disorders with congenital malformations related to impaired fetal movement.
In the patients with lung biopsy but without autopsy (D9 and D10), information related to other malformations was based on clinical and/or imaging observations without pathologic confirmation; for those with neither lung biopsy nor autopsy (D2, D5, and D6), lung histology remains unknown and information related to other malformations is based on clinical and/or imaging observations only.
Congenital malformations are increasingly contributing to overall infant mortality in developed countries such as the United States [ 5], where 20% of infant deaths in 2001 were related to congenital malformations [ 6].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com