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The mishaps were grouped into equipment related, patient related, line related and miscellaneous groups[1].
This suggests that genomic prediction using only information from a distantly related line or breed should be avoided.
In some cases, when adding a distantly related line, the linear models showed a slight decrease in performance, while non-linear models generally showed no change in accuracy.
A distantly related line of research is the modeling of nucleosome positions with the expectation that transcription factor binding sites avoid these positions [ 16- 18].
Using only data from a distantly related line for prediction with a linear model resulted sometimes in -small positive predictive correlations, in a few cases in considerable negative predictive correlations, and sometimes in predictions with very large bias.
Using one line to predict performance in another closely related line, yielded similar prediction accuracies with the RBF and the considered linear models, which suggests that the genotypes of closely related lines share some structural similarities.
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We identified 99 related CC samples that define 46 sets of related lines (Table S3).
No resistance to CPA was found in this pair of closely related lines and neither in two other pairs of closely related lines (Mogul/Borung and Cyprus/Caliph), [ 20].
More recently, the increased availability of SSR markers has enabled QTL analysis using populations between closely related lines, such as between temperate japonica lines.
Some are produced as "lines" that are produced by repeated self-fertilization or inbreeding or "multilines" that are made up of several closely related lines.
These resources provide thousands of SNP markers between almost any two lines of the thousands of Arabidopsis (closely related lines will have fewer SNPs).
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