As another example, evolutionary divergence in both C and O content were negatively related to divergence in GC content on EPC3, which reflected our findings within proteomes and supports previous findings among whole proteomes of other taxa [ 8, 14, 15].
Heterologous hybridization to study gene expression profiles has been validated between closely related species (divergence time < 10 Mya), and consistent data are also obtained for less closely related taxa (divergence time ~65 Mya; [ 28]).
Dermochelyids and cheloniids are distantly related; their divergence from one another took place between 100 million and 150 million years ago.
Such a model is further supported by monozygotic twin studies that point to age and environmentally related epigenetic divergence as the cause of discordant disease status [9], [10].
Nei has shown that genetic distance (D) is directly related to divergence time.
The data suggested the low contribution of mobile elements to sucrose related expression divergence either within BT×623 or Keller.
Second, sequence features such as the local GC content appear to be strongly related to divergence in avian genomes.
A framework to specifically analyse recombining genes is essential as nuclear genes, which are widely used in studies related to divergence and speciation, are subject to recombination.
They are more refractory to lateral gene transfers and usually present in a single copy in genomes, which avoids recombination and issues related to divergence between copies (Case et al. 2007; Adekambi et al. 2009).
However, there is neither adequate software for, nor study on, MSAs for detection of polymorphic regions and discrepancies (beyond single nucleotide dissimilarities) that would provide a numerical score related to divergence significance.
The total number of orthologs found between guppy and other species was related to divergence between the species (with the exception of medaka, Oryzias latipes, possibly due to the smaller size of the medaka protein database).
