Sentence examples for relapse and progression from inspiring English sources
Cytogenetic data suggest that acute myeloid leukemia (AML) develops through a process of branching evolution, especially during relapse and progression.
While platinum-based chemotherapeutic regimens have proven effective against highly proliferative malignant tumors, significant relapse and progression rates as well as decreased overall survival are still observed.
Highly clonogenic CSC have been identified in several human malignancies, including MM, and their combined resistance to chemotherapy and enhanced growth potential suggests that they may be responsible for disease relapse and progression [2], [3].
Reports describe relapse and progression (both metabolic and angiographic) despite immunosuppressive therapy [ 62, 104– 106].
Firstly, the definitions of the end point of interest, especially of relapse and progression, need validation.
However, many patients experience disease relapse and progression despite such treatment.
Interferon beta is commonly used to treat patients with relapsing-remitting multiple sclerosis; however, the treatment is only partially effective in reducing relapses and progression of disability.
The aim of this study was to evaluate the efficacy and safety of teriflunomide in reducing the frequency of relapses and progression of physical disability in patients with relapsing multiple sclerosis (RMS).
Because a majority of anti-cancer drugs target actively dividing (cycling) cells, quiescent CSC remain alive and may be the cause for relapses and progression of cancer.
Our findings raise the possibility that a defective PCr metabolism in astrocytes might contribute to the degeneration of oligodendrocytes and axons in MS. Relapses and progression are the two basic clinical courses of multiple sclerosis (MS), which is traditionally viewed as a T-cell driven autoimmune disease against myelin.
The dissociation between relapses and progression implies that relapses (except possibly during Years 1 and 2) are not a valid outcome surrogate for the late disability constituting the main social, medical and economic impact of multiple sclerosis.
