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Exact(2)
It is important not to overemphasize this finding given the non-signifcance, but it is important not to reject an effect out of hand in an underpowered study.
As SINF is the reciprocal of the variance in the meta-analysis, say, it follows that in meta-analyses with, the amount of information may eventually suffice to detect, or reject, an effect size of δ, without yet having reached HIS or DIS.
Similar(57)
The reduced pool of free men has also encouraged many women to accept marriage proposals from men they would have otherwise rejected, an effect that has been shown to be sufficient to shift the economic advantage of marriage away from women and toward men.
A number of human studies suggested that the risk SNPs in FTO associate with increases in food intake [16] [21], and rejected an effect on energy expenditure [18] [20], [22].
This would be a kind of a post hoc analysis of the information needed to detect or reject an intervention effect suggested by data already available.
We calculated the required information size to detect or reject an intervention effect of a 10% relative risk reduction with a risk of a type II error of 20% (power of 80%).
On the basis of pre-determined criteria, 13 we initially calculated the required information size to detect or reject an intervention effect of a 10% relative risk reduction with a risk of a type II error of 20% (power of 80%).
The estimation of a required information size for a meta-analysis in order to detect or reject an anticipated intervention effect on a binary outcome measure should be considered based on reasonable assumptions.
The estimation of a required IS for a meta-analysis to detect or reject an anticipated intervention effect on a binary outcome measure should be considered based on reasonable assumptions.
There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect.
The assumption that the IS required for a reliable and conclusive fixed-effect meta-analysis should be as large as the SS of a single well-powered randomised clinical trial to detect or reject an anticipated intervention effect [ 2- 4] may not be necessary in some instances.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com