5 Recent sequencing studies of pancreatic cancer have reinforced the complexity and heterogeneity of this disease.
These data, together with our findings on the value of MTHFR as a predictor of toxicity but not efficacy, reinforce the complexity of the impact of these genetic changes in predicting tailored chemotherapy treatments.
Nonetheless, they demonstrate the concept that significant variability in patient response to T2D therapeutic agents is a result of genetic variation and reinforce the complexity of choosing the most effective therapies for individual patients.
Others felt that after being trained with the VP, they became more open to ask people about their stories and to have full assessment of the patient's status physical, emotional, social and spiritual, which reinforces the complexity of patients.
Although the high figure may not be surprising given what we know about patient safety in general practice, 5 it does reinforce the complexity of such systems and highlights the potential difficulties faced by extremely busy GP teams in coping with everyday work related to the management of test results.
The consistencies between the current findings and those of international studies with different compensation systems, reinforce the complexities of certification and RTW.
However, our findings broadly concur with these previous studies, reinforcing both the complexity and range of issues which are likely to affect bioenergy feedstock supply from UK farmers.
This overlapping of biological events across wound healing phases is consistent with current understanding in the general literature (Gurtner et al., 2008; Martin, 1997) and reinforces the dynamic complexity of tissue repair in the VF microenvironment.
Furthermore, this quality of spatial mystery is compounded and reinforced by the complexity of the garden space.
Thus the differences observed between French and Spanish patients in the present study, reinforced by the complexity of the role played by cultural features in the response style bias, suggest that the country effect should be systematically tested when using the FGVS.
