These miRNAs may reinforce repression of Polycomb-bound genes as well as act on an entirely different set of differentiation targets.
Wagner scholar Paul Lawrence Rose insists that, in the allegorical scheme, "Jews are the agent of law, inhibiting the freedom to be human; they're the agents of capitalism, reinforcing repression; and domination, that's seen as a Jewish thing – the Ring gives the holder power over the world".
The MEE2-interacting factor or complex MIF may bind downstream of the TSS to reinforce repression and/or to prevent or reduce leaky transcription from silenced loci.
However, only a minority of CpG islands in promoter regions are methylated, and it remains unclear whether DNA methylation plays a general causal role in gene silencing, or instead reinforces repression that was established through other chromatin-based mechanisms.
The promoter histone deacetylation has been proposed to enhance further binding of Cyc8 Tup1 thereby reinforcing transcription repression of target genes [31].
By analogy with B. subtilis, the action of ParJ in causing ParA polymers to dissociate may lead to inhibition of DnaA, reinforcing the repression of further DNA replication (but there is no published evidence of a ParA-DnaA interaction in any actinobacteria).
The Capitol's creepy President Snow Donald Sutherlandd) is trying to reinforce the repression of the districts by forcing the 99percenttoto watch their teens tear each other to death every year.
When DILP2 secretion is reduced, the fat body will further induce dFOXO and thus reinforce the repression of dilp2 in the IPC.
This cycle is the core of the so-called 'Ping-pong' model, a feed-forward loop that amplifies the piRNA population and is thought to reinforce the repression of active transposons dispersed in the genome (Brennecke et al, 2007; Gunawardane et al, 2007).
Will it reinforce Mr. Mubarak's repression of a transition to a new order in which the aspirations of the protesters — fed up with poverty, lack of jobs and education, the excesses of the elite, official corruption and government repression — will be addressed?
