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Higher levels of proinflammatory CSF IFNγ were associated with more rapid rates of fungal clearance during treatment [ 17, 19] and lower fungal burdens at presentation, demonstrating the importance of IFN-γ in the protective immune response, and reinforcing the rationale for augmentation of proinflammatory responses with IFN-γ immunotherapy as a therapeutic approach [ 16].
"People have actually proposed both of those as drug targets before, but this really reinforces the rationale behind that idea".
This reinforces the rationale for studying the evolution of this policy field in different nation-state settings.
The potential risk of haematoma associated with regional anaesthesia techniques [12] in orthopaedic patients, reinforces the rationale for disruption in antiplatelet therapy with ensuing delay in surgery.
The results from this study, supported by previous experimental evidence, confirms that bovines are the major reservoir host of human schistosomiasis in the lake and marshland regions of southern China, and reinforce the rationale for the development and deployment of a transmission blocking anti-S.
These results reinforce the rationale for targeting B cells and/or BAFF in SSc.
These results reinforce the rationale for RCTs carrying the greatest weight when applying evidence to medical decision making.
This observation reinforces the rationale behind the current pursuit of newer, highly sensitive circulating markers for recurrence.
In any case, the results of this study reinforce the rationale for a study of citrulline supplementation in critically ill patients.
The low event rates over a prolonged time reinforce the rationale for aggressive treatment of younger women who have higher event rates (Joslyn, 2006) compared with older women.
We interpret the high sensitivity of our method in three ways; first it reinforces the rationale that GWAS with metabolomic phenotypes provides a functional approach to the study of human genetic variation [ 1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com