Sentence examples for reinforcing a role from inspiring English sources

We show that BbCRASP-2 is ubiquitously expressed in diverse murine tissues, but not in ticks, reinforcing a role of BbCRASP-2 in conferring B. burgdorferi defense against persistent host immune threats, such as complement.

However, the fifth screen listed is a screen for increased Rad52 DNA repair centers (6), reinforcing a role for the SAC in preventing DNA damage (19, 20).

DOI: http://dx.doi.org/10.7554/eLife.00969.025 The recently updated combination trial of the BRAFi dabrafenib and MEKi trametinib shows a low 7% cSCC rate in 54 patients, (Flaherty et al., 2012) suggesting that combined MEK inhibition can reduce, but not eliminate cSCC formation, nevertheless reinforcing a role for paradoxical ERK activation (Su et al., 2012).

To further reinforce a role of Sei1 in β-cells, we evaluated the expression of Sei1, Sertad2 and Sertad3 in isolated pancreatic islets (being Sertad2 the closest paralog of Sei1).

To further reinforce a role for eEF1γ in RNA metabolism, Fan et al. demonstrated in Drosophila that eEF1γ activity is required for the viability of both the whole animal and individual cells, emphasising that recessive lethality occurs during early larval development.

Furthermore, the difference between WT and ChemR23−/− mice is quite striking and reinforces a role for the ChemR23-endogenous chemerin pathway in the modulation of the innate immune response in vivo.

These effects were reversed with the introduction of a VDR antagonist, reinforcing a key role of vitamin D in this signaling mechanism.

The MSP results for island 4 (Table 1b) showed a statistical correlation with three variables related to metastasis, reinforcing a probable role for island 4 in the metastatic process.

Our work supports models of CRPC where there is a persistent reliance of prostate cancer cells on AR signalling and AR ligands, reinforcing a mechanistic role for newer therapies that target testosterone and highlights a novel androgen catabolism pathway for target development.

A recent study showed that the recruitment of clathrin is responsible for concentrating Hrs in these endosomal microdomains, reinforcing an active role for clathrin in protein retention (Raiborg et al. 2006).

Furthermore, studies in NHPs clearly showed that CV disease occurs in the absence of ART thus reinforcing an independent role of SIV infection in the development of CV disease [ 33].