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Because tolerogenic vaccines contain native myelin epitopes, tolerogenic vaccination would predictably reinforce regulatory T cell function and the low efficiency interactions that promote tolerance rather than immunity, even after differentiation of the conventional myelin-reactive T cells into memory and effector subsets.
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Our approach could reinforce the regulatory program by the expression of FOXP3, or other regulatory genes in our expression cassette.
These findings link the flagellar filaments with the overall architecture of the biofilm and reinforce the regulatory role for flagellar biosynthesis in the coordination of transcription of the other matrix elements.
Combining all of these regulators at a particular target likely reinforces regulatory patterns at specific cell densities, further ensuring the commitment to the LCD or HCD programme.
Reinforcing the regulatory apparatus of the nation's economy that has collapsed under this administration is indeed one of the most important challenges facing us today ("After the Fed," editorial, Jan . 31.
However, health workforce responsiveness is hampered by historic models of role delineation which are strongly socially entrenched and reinforced by regulatory and funding models.
Nevertheless, PTP1B deficiency protects against damage in hepatocytes in culture and in whole liver, reinforcing the regulatory role of this phosphatase in multiple molecular mechanisms triggered in response to APAP in distinct liver cells.
Since Nanog is an important pluripotency factor, it is highly likely that the overexpression of Nanog in ESCs may reinforce the pluripotency regulatory circuit, or stem cell properties, of ESCs.
Regardless, there should be close collaboration between the licensing agency and the accreditation body, in order to reinforce compliance with regulatory requirements and better enable sustainability of the AO [ 13- 17].
Indeed, if health care becomes a primary location for collecting the phenotypic and genetic data needed to create learning systems for research and clinical care, we need to reinforce the self-regulatory codes of ethics of genomic researchers and clinicians with legally recognized human rights, that is, a co-regulatory system.
These results reinforce the idea that regulatory mechanisms controlling temporal colinearity are the major constraints that maintain an intact ParaHox cluster [ 7].
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