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Interleukin-21 is required to reinforce differentiation of Th17 cells, and it plays a critical role in Th17-dependent autoimmune diseases [ 46].
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"We're moving to the next phase," he added, "and the objective is very clear: to reinforce our differentiation, creating more distance between us and our competitors".
Absolutely not! Hardware, if executed correctly, will create a moat around software and reinforce the differentiation of a verticalized IoT startup.
The very symbols by which we imagine our community are symbols of that community, and it is that self-referencing that creates a critical feedback loop back to the community and reinforces its differentiation.
The remarkable nesting philopatric behaviour of the Puffinus shearwaters (e.g., [23] [25]) could have reinforced such differentiation.
Interestingly, these enhancer RNAs (eRNAs) seem to provide a positive feedback mechanism to reinforce the myogenic differentiation commitment upon satellite cell activation.
Many studies showed that the change in the expression of a single microRNA can reinforce single lineage differentiation pathway into already committed cells or into progenitors grown in unilineage conditions.
We further show that BMP acts prior to and independently of Cdh1 to prime pluripotent cells for mesoderm differentiation, thus helping to reinforce the block to neural differentiation.
Assuming that inhibitors of MAPKs may act in stomata lineage to prevent epidermal cell differentiation and reinforce the stomata lineage we next tested the ectopic constitutive expression of each of these PP2Cs in Arabidopsis plants and searched for stomata developmental phenotypes.
In this scenario, genetic mutations in stem cells may influence programs for differentiation and/or reinforce programs for self-renewal.
We suggested that selection on this network enabled, or reinforced, a temporal differentiation between worker bees so they first labor inside the nest and later forage [22].
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